Clinical significance of bone changes in osteoarthritis
نویسندگان
چکیده
منابع مشابه
Clinical and Pathophysiologic Significance of MRI Identified Bone Marrow Lesions Associated with Knee Osteoarthritis
Knee osteoarthritis (OA) affects the joint beyond just the articular cartilage. Specifically, magnetic resonance imagingidentifiedbone marrow lesions (BML) in the subchondral bone have both clinical and pathophysiological significance.Compared to joint space narrowing on traditional radiographs, the presence of BMLs has been better correlated withseverity of clinical symptoms ...
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OBJECTIVE To test the hypothesis that changes in subchondral bone are significantly different among three canine models of osteoarthritis (OA). DESIGN In 21 purpose-bred mongrel dogs, OA was induced in one knee joint via either anterior cruciate ligament transection (ACLt; n = 5), medial femoral condylar groove creation (GR; n = 6), or medial meniscal release (MR; n = 5). Five dogs that had s...
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ژورنال
عنوان ژورنال: Therapeutic Advances in Musculoskeletal Disease
سال: 2012
ISSN: 1759-720X,1759-7218
DOI: 10.1177/1759720x12437354